Role of Glycolic and Salicylic Acid Chemical Peel in the Management of Post-acne Pigmentation: A Literature Review
Bharathi Ravikumar, Indra Devi
Keywords :
Chemical peeling, Glycolic acid, Post-acne hyperpigmentation, Salicylic acid
Citation Information :
Ravikumar B, Devi I. Role of Glycolic and Salicylic Acid Chemical Peel in the Management of Post-acne Pigmentation: A Literature Review. 2021; 10 (1):8-11.
Chemical peeling is a process wherein one or more chemical agents are applied to the skin. It causes partial destruction of the epidermis or dermis with exfoliation or desquamation followed by resurfacing of the epidermis and remodeling of the collagen and elastic fibers. It is a type of controlled cosmetic chemical burn which is one of the treatments for acne and post-acne pigmentation. Post-acne hyperpigmentation (PAH) is very common in acne patients which can occur in all skin types, although it is more common in dark skin types which affects both men and women equally. Many studies have been conducted for post-acne pigmentation by combining chemical peeling with lasers or with topical medications. Only a few studies have reported the efficacy of chemical peeling alone in the treatment of post-acne pigmentation. Thus, this review focuses on the efficacy of glycolic and salicylic acid chemical peels used in the management of post-inflammatory pigmentation.
Kircik LH. Efficacy and safety of azelaic acid (AzA) gel 15% in the treatment of post-inflammatory hyperpigmentation and acne: a 16-week, baseline-controlled study. J Drugs Dermatol 2011;10(6):586–590.
Matarasso SL, Glogau RG, Markey AC. Wood's lamp for super-ficial chemical peels. J Am Acad Dermatol 1994;30(6):988–992. DOI: 10.1016/s0190-9622(94)70124-5.
Woolery-Lloyd H, Kammer JN. Treatment of hyperpigmentation. Semin Cutan Med Surg 2011;30(3):171–175. DOI: 10.1016/j.sder.2011.06.004.
Rendon MI, Berson DS, Cohen JL, Roberts WE, Starker I, Wang B. Evidence and considerations in the application of chemical peels in skin disorders and aesthetic resurfacing. J Clin Aesthet Dermatol 2010;3(7):32.
Davis EC, Callender VD. Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin of color. J Clin Aesthet Dermatol 2010;3(7):20–31.
Akamutsu H, Horio T, Hattori K. Increased hydrogen peroxide generation by neutrophils from patients with acne inflammation. Int J Dermatol 2003;42(5):366–369. DOI: 10.1046/j.1365-4362.2003.01540.x.
Hourblin V, Nouveau S, Roy N, de Lacharrière O. Skin complexion and pigmentary disorders in facial skin of 1204 women in 4 Indian cities. Indian J Dermatol Venereol Leprol 2014;80(5):395–401. DOI: 10.4103/0378-6323.140290.
Grimes PE. Management of hyperpigmentation in darker racial ethnic groups. Semin Cutan Med Surg 2009;28(2):77–85. DOI: 10.1016/j.sder.2009.04.001.
Fabbrocini GDP, De Padova MP, Tosti A. Chemical peels: what's new and what isn't new but still works well. Facial Plast Surg 2009;25(5):329–336. DOI: 10.1055/s-0029-1243082.
Sharad J. Glycolic acid peel therapy—a current review. Clin Cosmet Investig Dermatol 2013;6:281–288. DOI: 10.2147/CCID.S34029.
Zakopoulou N, Kontochristopoulos G. Superficial chemical peels. J Cosmet Dermatol 2006;5(3):246–253. DOI: 10.1111/j.1473-2165.2006.00254.x.
Boer J, Jemec GB. Resorcinol peels as a possible self-treatmentof painful nodules in hidradenitis suppurativa. Clin Exp Dermatol 2010;35(1):36–40. DOI: 10.1111/j.1365-2230.2009.03377.x.
Strauss JS, Krowchuk DP, Leyden JJ, et al. Guidelines of care for acne vulgaris management. J Am Acad Dermatol 2007;56(4):651–663. DOI: 10.1016/j.jaad.2006.08.048.
Sachdeva S. Comparative efficacy of 10-20% trichloroacetic acid and 35-70% glycolic acid peel in 60 cases of melasma, freckles, lentigenes and post inflammatory hperpigmentation. J Pak Assoc Derma 2006;16:76–80.
Sacchidanand S, Shetty AB, Leelavathy B. Efficacy of 15% trichloroacetic acid and 50% glycolic acid peel in the treatment of frictional melanosis: a comparative study. J Cutan Aesthet Surg 2015;8(1):37–41. DOI: 10.4103/0974-2077.155078.
Burns RL, Prevost-Blank PL, Laury MA, Laury TB, Faira DT, Fiverson AP. Glycolic acid peels for post-inflammatory hyperpigmenatation in black patients: a comparative study. Dermatol Surg 1997;23(3):171–174. DOI: 10.1111/j.1524-4725.1997.tb00014.x.
Grover C, Reddu BS. The therapeutic value of glycolic acid peels in dermatology. Indian J Dermatol Venereol Leprol 2003;69(2):148–150.
Garg VK, Sinha S, Sarkar R. Glycolic acid peels versus salicylicmandelic acid peels in active acne vulgaris and post-acne scarring and hyperpigmentation: a comparative study. Dermatol Surg 2009;35(1):59–65. DOI: 10.1111/j.1524-4725.2008.34383.x.
Sarkar R, Parmar NV, Kapoor S. Treatment of postinflammatory hyperpigmentation with a combination of glycolic acid peels and a topical regimen in dark-skinned patients: a comparative study. Dermatol Surg 2017;43(4):566–573. DOI: 10.1097/DSS.0000000000001007.
Joshi SS, Boone SL, Alam M, Yoo S, White L, Rademaker A, et al. Effectiveness, safety, and effect on quality of life of topical salicylic acid peels for treatment of postinflammatory hyperpigmentation in dark skin. Dermatol Surg 2009;35(4):638–644. DOI: 10.1111/j.1524-4725.2009.01103.x.
Grimes PE. The safety and efficacy of salicylic acid chemical peel in darker racial-ethnic groups. Dermatol Surg 1999;25(1):18–22. DOI: 10.1046/j.1524-4725.1999.08145.x.
Bari AU, Iqbal Z, Rahman SB. Tolerance and safety of superficial chemical peeling with salicyclic acid in various facial dermatoses. Indian J Dermatol Venereol Leprol 2005;71(2):87–90. DOI: 10.4103/0378-6323.13990.
Ahn HH, Kim IH. Whitening effect of salicyclic acid peels in Asian patients. Dermatol Surg 2006;32(3):372–375. DOI: 10.1111/j.1524-4725.2006.32075.x.
Ali BMM, Gheida SF, Mahdy NAE, Sadek SN. Evaluation of salicylic acid peeling in comparison with topical tretinoin in the treatment of postinflammatory hyperpigmentation. J Cosmet Dermatol 2016;16:52–56.
